diff --git a/cmake/QtAutoDetectHelpers.cmake b/cmake/QtAutoDetectHelpers.cmake
index bef1d876bf5..fe6087748d6 100644
--- a/cmake/QtAutoDetectHelpers.cmake
+++ b/cmake/QtAutoDetectHelpers.cmake
@@ -248,6 +248,11 @@ function(qt_auto_detect_apple)
 
     if(QT_APPLE_SDK)
         set(CMAKE_OSX_SYSROOT "${QT_APPLE_SDK}" CACHE STRING "")
+    elseif(NOT CMAKE_SYSTEM_NAME)
+        # Persist SDK name for macOS builds, since CMake 4.x will pick arbitrary
+        # SDK paths, ignoring xcode-select, if not given an explicit SDK.
+        _qt_internal_get_apple_sdk_name(sdk_name)
+        set(CMAKE_OSX_SYSROOT "${sdk_name}" CACHE STRING "")
     endif()
 
     if(CMAKE_SYSTEM_NAME STREQUAL iOS OR CMAKE_SYSTEM_NAME STREQUAL visionOS)
diff --git a/cmake/QtToolchainHelpers.cmake b/cmake/QtToolchainHelpers.cmake
index 1ee064bd7a9..c006f1b677a 100644
--- a/cmake/QtToolchainHelpers.cmake
+++ b/cmake/QtToolchainHelpers.cmake
@@ -168,7 +168,7 @@ endif()")
         set(cmake_sysroot_name "$CACHE{CMAKE_OSX_SYSROOT}")
 
         list(LENGTH CMAKE_OSX_ARCHITECTURES _qt_osx_architectures_count)
-        if(cmake_sysroot_name AND NOT _qt_osx_architectures_count GREATER 1 AND UIKIT)
+        if(cmake_sysroot_name AND (MACOS OR (UIKIT AND NOT _qt_osx_architectures_count GREATER 1)))
             list(APPEND init_platform "
 if(NOT DEFINED CMAKE_OSX_SYSROOT)
     set(CMAKE_OSX_SYSROOT \"${cmake_sysroot_name}\" CACHE STRING \"\")